In the Bible there are many symbols, and one of the main sets of symbolism is in regard to those who are family and those who are strangers (not family).
The family of God is made up of those who believe in the Savior, the Messiah, the Son of God, whom we know as Jesus Christ.
All others who do not believe in Christ are described as strangers or people who are not known.
When God made this world, He made it for believers or for His family members. It originally belonged to God, in fact the entire universe belonged to God, was never given to the angels, and is there for an inheritance for His children.
Generally only family inherit from the parent. Strangers or unknown people do not inherit from your family.
Since believers are family then only believers are legitimate heirs. Strangers are not family and are not heirs.
Typically when you own something, you tend to take god care of it. At least a responsible person does. But when strangers acquire your stuff, they do not take good care of it. And here is our picture in this verse.
By not being responsible in their spiritual lives, the country, the cities, the land, all that you have, are destroyed as by strangers. When an invading army comes into your space, they take and destroy, and that is exactly what unbelievers are. That is also what negative believers are, folks that do not take care of their possessions.
By not taking care of your soul (the previous couple of verses) you will lose the health of your soul, and that overflows into the physical world. Your possessions, your home, your country, all that you have, will deteriorate.
Desolate, means total ruin.
Land refers to all of the production of the land, or all that you have.
Strangers, means foreigners, alienated or estranged people. People who are in a separate category as you (not family, people who are unknown, people that you do not know, people that God does not know – no spiritual life).
If you lack a legitimate spiritual life, then whatever you have, whoever you are, will come to nothing. You will be spending your entire life accomplishing absolutely nothing. For when you go to heaven, assuming that you are a believer, then you go to heaven with nothing.
If you are an unbeliever, then you don’t even go to heaven. Your nothing even gets worse in the Lake of Fire.